Irradiated mouse testes efficiently support spermatogenesis derived from donor germ cells of mice and rats.

@article{Zhang2006IrradiatedMT,
  title={Irradiated mouse testes efficiently support spermatogenesis derived from donor germ cells of mice and rats.},
  author={Zhen Zhang and Shan H. Shao and Marvin L. Meistrich},
  journal={Journal of andrology},
  year={2006},
  volume={27 3},
  pages={365-75}
}
Testicular cell transplantation has been widely used to investigate the biology of spermatogonial stem cells, production of transgenic animals, and restoration of fertility in rodent models. One critical step in successful transplantation is the preparation of the recipient testes. Busulfan has been widely used, but irradiation has been often suggested as… CONTINUE READING