Irradiated esophageal cells are protected from radiation-induced recombination by MnSOD gene therapy.

@article{Niu2010IrradiatedEC,
  title={Irradiated esophageal cells are protected from radiation-induced recombination by MnSOD gene therapy.},
  author={Yunyun Niu and Hong Wang and Dominika M Wiktor-Brown and Rebecca E Rugo and Hongmei Shen and Mohammed Saiful Huq and Bevin P. Engelward and Michael P. Epperly and Joel S. Greenberger},
  journal={Radiation research},
  year={2010},
  volume={173 4},
  pages={453-61}
}
Radiation-induced DNA damage is a precursor to mutagenesis and cytotoxicity. During radiotherapy, exposure of healthy tissues can lead to severe side effects. We explored the potential of mitochondrial SOD (MnSOD) gene therapy to protect esophageal, pancreatic and bone marrow cells from radiation-induced genomic instability. Specifically, we measured the… CONTINUE READING