Iron uptake from ferrioxamine and from ferrirhizoferrin by germinating spores of Rhizopus microsporus.

@article{Locht1994IronUF,
  title={Iron uptake from ferrioxamine and from ferrirhizoferrin by germinating spores of Rhizopus microsporus.},
  author={M de Locht and Johan R. Boelaert and Yves Schneider},
  journal={Biochemical pharmacology},
  year={1994},
  volume={47 10},
  pages={1843-50}
}
Mucormycosis caused by the fungus Rhizopus has been documented in iron overloaded patients and more particularly in dialysis patients, both when treated with desferrioxamine B (DFO). This iron and aluminium chelator is thought to play a role in the pathogenesis of this infection. We therefore investigated in vitro the cellular pharmacology of iron chelated by DFO in the fungus Rhizopus. In a medium, designed for fungal cultivation, Rhizopus microsporus var. rhizopodiformis takes up iron from… CONTINUE READING
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