Iron transport and regulation, cell signalling and genomics: lessons from Escherichia coli and Pseudomonas.

@article{Visca2002IronTA,
  title={Iron transport and regulation, cell signalling and genomics: lessons from Escherichia coli and Pseudomonas.},
  author={Paolo Visca and Livia Leoni and Megan J. Wilson and Iain L Lamont},
  journal={Molecular microbiology},
  year={2002},
  volume={45 5},
  pages={1177-90}
}
A variety of bacterial species secrete and take up chelating compounds that enable acquisition of iron (siderophores). It has become clear that a common feature in regulation of different iron acquisition systems is the involvement of alternative sigma factor proteins of the extracytoplasmic function (ECF) family. Two of these proteins, PvdS from Pseudomonas aeruginosa and FecI from Escherichia coli K-12, have been studied extensively. PvdS directs transcription of genes required for the… CONTINUE READING