Iron-sulfur cluster assembly: NifU-directed activation of the nitrogenase Fe protein.

@article{Santos2004IronsulfurCA,
  title={Iron-sulfur cluster assembly: NifU-directed activation of the nitrogenase Fe protein.},
  author={Patricia C Dos Santos and Archer D Smith and Jeverson Frazzon and Valerie L. Cash and Michael K. Johnson and Dennis R Dean},
  journal={The Journal of biological chemistry},
  year={2004},
  volume={279 19},
  pages={19705-11}
}
The NifU protein is a homodimer that is proposed to provide a molecular scaffold for the assembly of [Fe-S] clusters uniquely destined for the maturation of the nitrogenase catalytic components. There are three domains contained within NifU, with the N-terminal domain exhibiting a high degree of primary sequence similarity to a related family of [Fe-S] cluster biosynthetic scaffolds designated IscU. The C-terminal domain of NifU exhibits sequence similarity to a second family of proposed [Fe-S… CONTINUE READING