Iron stores and serum transferrin receptor levels during recombinant human erythropoietin treatment of anemia in rheumatoid arthritis

@article{Vreugdenhil1992IronSA,
  title={Iron stores and serum transferrin receptor levels during recombinant human erythropoietin treatment of anemia in rheumatoid arthritis},
  author={Gerard Vreugdenhil and Bernhard Manger and Ch. van Nieuwenhuizen and R A Richard Feelders and Henk G. van Eijk and Antonius J G Swaak},
  journal={Annals of Hematology},
  year={1992},
  volume={65},
  pages={265-268}
}
Ten rheumatoid arthritis (RA) patients with anemia of chronic disorders (ACD) were treated with recombinant human erythropoietin (r-Hu-Epo) using a dose of 250 U/kg s.c. 3 times a week for 6 weeks, in order to evaluate its effects on the anemia, iron stores, and serum-soluble transferrin receptor (sTfR) levels. All patients showed a rise in hemoglobin (Hb). Median Hb increased from 5.9 (5.5–7.0) at baseline to 6.7 (5.8–7.8) at 3 weeks and to 7.2 (5.9–8.5) mmol/l at 6 weeks during treatment… CONTINUE READING