Iron status and the outcome of HIV infection: an overview.

@article{Gordeuk2001IronSA,
  title={Iron status and the outcome of HIV infection: an overview.},
  author={Victor R. Gordeuk and Joris Richard Delanghe and Michel R. Langlois and Johan R. Boelaert},
  journal={Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology},
  year={2001},
  volume={20 3},
  pages={
          111-5
        }
}
  • V. Gordeuk, J. Delanghe, J. Boelaert
  • Published 1 February 2001
  • Medicine, Biology
  • Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Iron status in HIV-1 infection: implications in disease pathology
TLDR
It could be inferred that derangement in iron metabolism, in addition to oxidative stress, might have contributed to the depletion of CD4+ T cell population in anti-retroviral naive HIV-1 positive and 50 sero-negative controls and this may result in poor prognosis of the disease.
Anemia and iron homeostasis in a cohort of HIV-infected patients in Indonesia
TLDR
High ferritin with low sTfR levels suggest that iron redistribution and low erythropoietic activity, rather than iron deficiency, contribute to anemia among HIV-infected patients in Indonesia and strongly related to mortality.
The Effects of Treatment on Serum Hepcidin and Iron Homeostasis in HIV-1-Infected In-dividuals
TLDR
HIV-1 infection affected serum hepcidin, iron and ferritin levels in the ART-naive group, and the different HAART regimens restored the levels of hepcIDin and iron homeostasis in HIV-1-infected individuals who have undetectable HIV- 1 RNA levels.
Elevated iron stores are associated with HIV disease severity and mortality among postpartum women in Zimbabwe
TLDR
The results are consistent with the hypothesis that high Fe stores have adverse consequences in HIV infection, and suggest that they occur at SF concentrations exceeding those consistent with adequate Fe nutriture.
Coinfection with HIV-1 Alleviates Iron Accumulation in Patients with Chronic Hepatitis C Virus Infection
TLDR
It is suggested that coinfection with HIV-1 alleviates iron accumulation caused by chronic HCV infection and helps understand the complexity of alternations in iron distribution in HCV/HIV-1-coinfected patients.
The association of serum ferritin and transferrin receptor concentrations with mortality in women with human immunodeficiency virus infection.
TLDR
Higher indirect measures ofIron status were associated with reduced survival among HAART-naive HIV-infected women and additional prospective studies with data on direct measures of iron status along with randomized trials are needed to elucidate the current equipoise over whether iron supplementation is beneficial by preventing anemia or harmful by increasing iron stores in HIV- infected women.
Short communication: high cellular iron levels are associated with increased HIV infection and replication.
TLDR
The levels of cellular iron in primary CD4(+) T cells are altered and it is shown that higher iron is associated with increased HIV infection and replication and that iron homeostasis may be a viable therapeutic target for HIV.
The effect of the host's iron status on tuberculosis.
TLDR
The host's iron status may be an important yet underevaluated factor in TB prevention and therapy and in TB vaccine design.
Iron supplementation for reducing morbidity and mortality in children with HIV.
TLDR
The evidence for iron supplementation for reducing morbidity and mortality in HIV-infected children is assessed to determine whether iron supplementation improves clinical, immunologic, and virologic outcomes in children infected with HIV.
Impaired Hematological Status Increases the Risk of Mortality among HIV-Infected Adults Initiating Antiretroviral Therapy in Tanzania.
TLDR
Anemia and both ID and elevated iron were associated with increased mortality among HIV-infected adults initiating HAART and dose of iron supplementation among HIV patients appear warranted.
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