Iron-sensitive fluorescent probes: monitoring intracellular iron pools.

  title={Iron-sensitive fluorescent probes: monitoring intracellular iron pools.},
  author={Yongmin Ma and Vincenzo Abbate and Robert C. Hider},
  journal={Metallomics : integrated biometal science},
  volume={7 2},
Several iron-sensitive fluorophores have been investigated in a range of cell types in order to quantify iron(II) levels in the cytosol and the cytoplasm. Both iron(II) and iron(III) cause fluorescence quenching of these probes and changes in cytosolic iron levels can be monitored in a reproducible manner. However the precise quantification of iron(II) in the cytosol is complicated by the uncertainty of the structure of many of the quenched species that exist under in vivo conditions. Precise… CONTINUE READING

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