Iron overload in renal failure patients: changes since the introduction of erythropoietin therapy.

@article{Eschbach1999IronOI,
  title={Iron overload in renal failure patients: changes since the introduction of erythropoietin therapy.},
  author={Joseph Wetherill Eschbach and John W See Adamson},
  journal={Kidney international. Supplement},
  year={1999},
  volume={69},
  pages={S35-43}
}
Iron overload was a common complication in patients with chronic renal failure treated with dialysis prior to the availability of recombinant human erythropoietin (rHuEPO) therapy. Iron overload was the result of hypoproliferative erythroid marrow function coupled with the need for frequent red blood cell transfusions to manage symptomatic anemia. The repetitive use of intravenous iron with or without the use of red blood cell transfusions also contributed to iron loading and was associated… CONTINUE READING