Iron overload in hematopoietic cell transplantation

  title={Iron overload in hematopoietic cell transplantation},
  author={Navneet S Majhail and Hillard M Lazarus and Linda Jean Burns},
  journal={Bone Marrow Transplantation},
Iron overload, primarily related to RBC transfusions, is a relatively common complication in hematopoietic cell transplant (HCT) recipients. Iron overload increases the risk of infections, veno-occlusive disease and hepatic dysfunction post transplant. Elevated pretransplant ferritin levels have been reported to increase the risk of nonrelapse mortality following HCT and might influence the risk of acute and chronic GVHD. Serum ferritin is sensitive but not specific for iron overload and is a… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 50 extracted citations


Publications referenced by this paper.
Showing 1-10 of 74 references

High prevalence of iron overload in adult survivors of allogeneic hematopoieitic cell transplantation

  • NS Majhail, TE Defor, B Kang, C Paley, HM Lazarus, LJ. Burns
  • Biol Blood Marrow Transplant
  • 2008

Elevated ferritin is associated with poorer survival following nonablative allogeneic transplantation

  • A Mahindra, R Sobecks, L Rybicki, S Brown, B Pohlman, M Kalaycio
  • Blood
  • 2007

Elevated pretransplant serum ferritin in autologous stem cell transplant

  • A Mahindra, B Bolwell, R Sobecks, L Rybicki, S Brown, B Pohlman
  • Blood
  • 2007

Similar Papers

Loading similar papers…