Iron overload causes osteoporosis in Thalassemia Major patients through interaction with TRPV 1 channels

Abstract

The pathogenesis of bone resorption in β-Thalassemia Major is multifactorial and our understanding of the underlying molecular and cellular mechanisms remains incomplete. Considering the emerging importance of the endocannabinoid/endovanilloid system in bone metabolism, examining a potential role for this system in the development of osteoporosis in… (More)

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