Iron overload, public health, and genetics: evaluating the evidence for hemochromatosis screening.

@article{Cogswell1998IronOP,
  title={Iron overload, public health, and genetics: evaluating the evidence for hemochromatosis screening.},
  author={Mary E Cogswell and Sharon M. McDonnell and Muin J. Khoury and Adele L. Franks and Laxman W Burke and GaryM. Brittenham},
  journal={Annals of internal medicine},
  year={1998},
  volume={129 11},
  pages={
          971-9
        }
}
As many as 1 million persons in the United States are affected by hemochromatosis, a genetic condition characterized by excess iron absorption and pathologic iron deposition in tissue [1]. If undetected and untreated, hemochromatosis can result in illness (such as cirrhosis, hepatoma, diabetes, cardiomyopathy, arthritis, arthropathy, and hypopituitarism with hypogonadism) and death. The identification and treatment of asymptomatic persons in whom iron measures are elevated but hemochromatosis… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 76 REFERENCES

Long-term survival in patients with hereditary hemochromatosis. Gastroenterology

  • C Niederau, R Fischer, A Purschel, W Stremmel, D Haussinger, G. Stroh- meyer
  • 1996
Highly Influential
9 Excerpts

A novel MHC class l-like gene is mutated in patients with hereditary 978 1 December

  • JN Feder, A Gnirke, W Thomas, Z Tsuchihashi, DA Ruddy, A Basava
  • Annals of Internal Medicine • Volume
  • 1998
Highly Influential
7 Excerpts

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