Iron load increases ferritin synthesis and secretion in adult human hepatocyte cultures.

@article{Lescoat1991IronLI,
  title={Iron load increases ferritin synthesis and secretion in adult human hepatocyte cultures.},
  author={G{\'e}rard Lescoat and N Hubert and Romain Moirand and Patrick J{\'e}go and Nicole Pasdeloup and Pierre Brissot},
  journal={Liver},
  year={1991},
  volume={11 1},
  pages={
          24-9
        }
}
In order to determine if iron load was able to stimulate specifically ferritin synthesis and secretion in adult human hepatocytes, primary cultures were submitted to increasing concentrations of ferric iron. The following results were obtained: 1. iron incorporation within the hepatocytes increased as a function of culture time and reached a high level after 48 h of treatment; 2. a dose-dependent significant stimulation of ferritin synthesis and secretion was observed when the medium iron… Expand
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Tese de doutoramento, Biologia (Biologia-Molecular), Universidade de Lisboa, Faculdade de Ciencias, 2015

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