Iron kinetics with emphasis on iron overload.


BODY IRON IN MAN is estimated at 35 to 45 mg/kg or a total of about 3 g.1 The major portion of body iron, some 30 mg/kg, is held in the circulating red cell mass and erythroid marrow as hemoglobin. The only other fraction of quantitative significance is storage iron, amounting to another 15 mg/kg in the adult male and varying from 0 to 10 mg/kg in the female. The manner in which body iron is maintained and its movement within the body become important in understanding anemia and iron overload states. For the purposes of this discussion, three aspects of iron exchange will be considered: exchange between man and his environment, internal iron exchange and, more specifically, storage iron exchange.

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Cite this paper

@article{Cook1973IronKW, title={Iron kinetics with emphasis on iron overload.}, author={James D. Cook and William E. Barry and Chaim M Hershko and Georges Fillet and Constance A. Finch}, journal={The American journal of pathology}, year={1973}, volume={72 2}, pages={337-44} }