Iron inhibits the nitric oxide synthesis elicited by asbestos in murine macrophages.

@article{Aldieri2001IronIT,
  title={Iron inhibits the nitric oxide synthesis elicited by asbestos in murine macrophages.},
  author={Elisabetta Aldieri and Dario Ghigo and Maura Tomatis and Laura Prandi and Ivana Fenoglio and Costanzo Costamagna and Gianpiero Pescarmona and Amalia Bosia and Bice Fubini},
  journal={Free radical biology & medicine},
  year={2001},
  volume={31 3},
  pages={412-7}
}
Crocidolite fibers stimulated nitric oxide synthase (NOS) activity and expression in glial and alveolar murine macrophages: this effect was inhibited by iron supplementation and enhanced by iron chelation. We suggest that in these cells crocidolite stimulates NOS expression by decreasing the iron bioavailability and activating an iron-sensitive transcription factor. 

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