Iron-induced oxidative stress modify tau phosphorylation patterns in hippocampal cell cultures

@article{Egaa2003IroninducedOS,
  title={Iron-induced oxidative stress modify tau phosphorylation patterns in hippocampal cell cultures},
  author={J. Ega{\~n}a and Cristian A Zambrano and Marco T. Nu{\~n}ez and Christian Gonz{\'a}lez-Billault and Ricardo Benjamin Maccioni},
  journal={Biometals},
  year={2003},
  volume={16},
  pages={215-223}
}
Oxidative stress phenomena have been related with the onset of neurodegenerative diseases. Particularly in Alzheimer Disease (AD), oxygen reactive species (ROS) and its derivatives can be found in brain samples of postmortem AD patients. However, the mechanisms by which oxygen reactive species can alter neuronal function are still not elucidated. There is a growing amount of evidence pointing to a role for mitochondrial damage as the source of free radicals involved in oxidative stress. Among… CONTINUE READING

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