Iron incorporation and haemoglobin synthesis in erythropoietic cells during the ontogenesis of the mouse.

@article{Schalekamp1975IronIA,
  title={Iron incorporation and haemoglobin synthesis in erythropoietic cells during the ontogenesis of the mouse.},
  author={Martin A D H Schalekamp and Paul R. Harrison and John Paul},
  journal={Journal of embryology and experimental morphology},
  year={1975},
  volume={34 2},
  pages={355-71}
}
Iron incorporation (59Fe) into erythropoietic cells from adult and foetal (11- to 15-day) peripheral blood and from foetal (12- to 15-day) livers has been investigated. Ion-exchange chromatography of haemolysates from such cells revealed two groups of 59Fe-containing proteins. The first group (X-fraction) was eluted from CMC-columns in the void volume and was highest in lysates of immature erythropoietic cells. This fraction contained a radiolabelled haemprotein of high molecular weight as well… CONTINUE READING
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