Iron deposition and increased alveolar septal capillary density in nonfibrotic lung tissue are associated with pulmonary hypertension in idiopathic pulmonary fibrosis

@inproceedings{Kim2010IronDA,
  title={Iron deposition and increased alveolar septal capillary density in nonfibrotic lung tissue are associated with pulmonary hypertension in idiopathic pulmonary fibrosis},
  author={Kyung Hee Kim and Fabien Maldonado and Jay H Ryu and Patrick W Eiken and Thomas E. Hartman and Brian J. Bartholmai and P. Anthony Decker and Eunhee Yi},
  booktitle={Respiratory research},
  year={2010}
}
BACKGROUND Early diagnosis of pulmonary hypertension (PH) in idiopathic pulmonary fibrosis (IPF) has potential prognostic and therapeutic implications but can be difficult due to the lack of specific clinical manifestations or accurate non-invasive tests. Histopathologic parameters correlating with PH in IPF are also not known. Remodeling of postcapillary pulmonary vessels has been reported in the nonfibrotic areas of explanted lungs from IPF patients. We hypothesized that iron deposition and… CONTINUE READING