Iron deficiency decreases dopamine D1 and D2 receptors in rat brain.

  title={Iron deficiency decreases dopamine D1 and D2 receptors in rat brain.},
  author={Keith M. Erikson and Byron C Jones and Ellen J Hess and Quanbin Zhang and John L. Beard},
  journal={Pharmacology, biochemistry, and behavior},
  volume={69 3-4},
Iron deficiency (ID) in early life is known to alter neurological development and functioning, but data regarding specific effects on dopamine biology are lacking. The objective of this study was to determine the extent of functional alterations in dopamine receptors in two dopaminergic tracts in young, growing, iron-deficient rats. Forty male and 40 female weanling Sprague-Dawley rats were fed either an iron-deficient (ID) diet or control (CN) diet for 6 weeks. ID decreased densities of D(1… CONTINUE READING
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Pollit E. Iron deficiency and cognitive function

  • RM Post, SRB Weiss, A Pert, TW. Uhde
  • rats. J Nutr
  • 2000

Long-term consequences of early iron deficiency on dopaminergic transmission

  • D Ben-Shachar, R Ashkenazi, MBH. Youdim
  • J Dev Neurosci
  • 1999

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