Iron-chelator complexes as iron sources for early developing human erythroid precursors.

Abstract

Developing erythroid cells are dependent on transferrin (Tf) to acquire iron in amounts sufficient for hemoglobin production. Previously, we showed that although these cells cannot grow in culture in the absence of Tf, ferritin (Ft) can substitute Tf to some extent and support the development of hemoglobin-containing cells. In the current study, we… (More)
DOI: 10.1016/j.trsl.2007.12.002

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