Iron-catalyzed cross-coupling of electron-deficient heterocycles and quinone with organoboron species via innate C-H functionalization: application in total synthesis of pyrazine alkaloid botryllazine A.

@article{Singh2013IroncatalyzedCO,
  title={Iron-catalyzed cross-coupling of electron-deficient heterocycles and quinone with organoboron species via innate C-H functionalization: application in total synthesis of pyrazine alkaloid botryllazine A.},
  author={Parvinder Pal Singh and Sravan Kumar Aithagani and Mahipal Yadav and Varun Pratap Singh and Ram A Vishwakarma},
  journal={The Journal of organic chemistry},
  year={2013},
  volume={78 6},
  pages={2639-48}
}
Here, we report an iron-catalyzed cross-coupling reaction of electron-deficient heterocycles and quinone with organoboron species via innate C-H functionalization. Iron(II) acetylacetonate along with oxidant (K2S2O8) and phase-transfer catalyst (TBAB) under open flask conditions efficiently catalyzed the cross-coupling of pyrazine with arylboronic acids and… CONTINUE READING