Iron and copper transport in yeast and its relevance to human disease.

Abstract

Recent progress in the field of copper and iron metabolism has resulted from a convergence of human and yeast genetics. The mechanisms of iron and copper transport are remarkably conserved between yeast and humans. Studies of the yeast homologs of human disease genes involved in metal homeostasis have shed light on the pathophysiology of these disorders.

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@article{Askwith1998IronAC, title={Iron and copper transport in yeast and its relevance to human disease.}, author={Candice C. Askwith and Jean Claude Kaplan}, journal={Trends in biochemical sciences}, year={1998}, volume={23 4}, pages={135-8} }