Iron and carbon monoxide attenuate degradation of plasmatic coagulation by Crotalus atrox venom.

Abstract

Hypofibrinogenemia is an important clinical consequence following envenomation by Crotalus species, usually attenuated or prevented by administration of antivenom. It has been determined that iron and carbon monoxide (CO) enhance fibrinogen as a thrombin substrate, likely secondary to conformational changes in molecular structure. We tested the hypothesis… (More)
DOI: 10.1097/MBC.0000000000000440

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Cite this paper

@article{Nielsen2016IronAC, title={Iron and carbon monoxide attenuate degradation of plasmatic coagulation by Crotalus atrox venom.}, author={Vance Girard Nielsen and L. Boyer}, journal={Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis}, year={2016}, volume={27 5}, pages={506-10} }