Iron and aluminum increase in the substantia nigra of patients with Parkinson's disease: an X-ray microanalysis.


The levels of different elements were studied by x-ray microanalysis in the substantia nigra and the central gray substance of patients with Parkinson's disease, progressive supranuclear palsy, and matched controls. In control brains, only iron, potassium, silicum, sodium, sulfur, and zinc were within the limit of detection of the technique. The abundance… (More)


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