Iron accumulation in the substantia nigra in rats visualized by ultrasound.

@article{Berg1999IronAI,
  title={Iron accumulation in the substantia nigra in rats visualized by ultrasound.},
  author={Daniela Berg and Christoph Grote and Wolf Dieter Rausch and Mathias Maeurer and Wolfgang Wesemann and Peter Franz Riederer and Georg Becker},
  journal={Ultrasound in medicine & biology},
  year={1999},
  volume={25 6},
  pages={901-4}
}
In recent studies, we have found a marked increase in substantia nigra (SN) echogenicity in patients with Parkinson's disease (PD) using transcranial ultrasound. Because a substantial body of evidence has accumulated indicating a selective elevation of iron in the SN from patients with PD, we set out to test the hypothesis that trace metals like iron could lead to the observed increase of SN echogenicity in PD. Rat brains were scanned after stereotactic injection of iron in different… CONTINUE READING
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