Iron Loading and Overloading due to Ineffective Erythropoiesis

@inproceedings{Tanno2010IronLA,
  title={Iron Loading and Overloading due to Ineffective Erythropoiesis},
  author={Toshihiko Tanno and Jeffery Lynn Miller},
  booktitle={Advances in hematology},
  year={2010}
}
Erythropoiesis describes the hematopoietic process of cell proliferation and differentiation that results in the production of mature circulating erythrocytes. Adult humans produce 200 billion erythrocytes daily, and approximately 1 billion iron molecules are incorporated into the hemoglobin contained within each erythrocyte. Thus, iron usage for the hemoglobin production is a primary regulator of plasma iron supply and demand. In many anemias, additional sources of iron from diet and tissue… CONTINUE READING

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