Iron–sulfur protein folds, iron–sulfur chemistry, and evolution

@article{Meyer2007IronsulfurPF,
  title={Iron–sulfur protein folds, iron–sulfur chemistry, and evolution},
  author={J. Meyer},
  journal={JBIC Journal of Biological Inorganic Chemistry},
  year={2007},
  volume={13},
  pages={157-170}
}
  • J. Meyer
  • Published 2007
  • Chemistry, Medicine
  • JBIC Journal of Biological Inorganic Chemistry
  • An inventory of unique local protein folds around Fe–S clusters has been derived from the analysis of protein structure databases. Nearly 50 such folds have been identified, and over 90% of them harbor low-potential [2Fe–2S]2+,+ or [4Fe–4S]2+,+ clusters. In contrast, high-potential Fe–S clusters, notwithstanding their structural diversity, occur in only three different protein folds. These observations suggest that the extant population of Fe–S protein folds has to a large extent been shaped in… CONTINUE READING

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