Iron–sulfur protein folds, iron–sulfur chemistry, and evolution

@article{Meyer2007IronsulfurPF,
  title={Iron–sulfur protein folds, iron–sulfur chemistry, and evolution},
  author={Jacques Meyer},
  journal={JBIC Journal of Biological Inorganic Chemistry},
  year={2007},
  volume={13},
  pages={157-170}
}
  • Jacques Meyer
  • Published 2007
  • Chemistry, Medicine
  • JBIC Journal of Biological Inorganic Chemistry
An inventory of unique local protein folds around Fe–S clusters has been derived from the analysis of protein structure databases. Nearly 50 such folds have been identified, and over 90% of them harbor low-potential [2Fe–2S]2+,+ or [4Fe–4S]2+,+ clusters. In contrast, high-potential Fe–S clusters, notwithstanding their structural diversity, occur in only three different protein folds. These observations suggest that the extant population of Fe–S protein folds has to a large extent been shaped in… Expand
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