Iron, the substantia nigra and related neurological disorders.

@article{Snyder2009IronTS,
  title={Iron, the substantia nigra and related neurological disorders.},
  author={Amanda M. Snyder and James R. Connor},
  journal={Biochimica et biophysica acta},
  year={2009},
  volume={1790 7},
  pages={606-14}
}
BACKGROUND Iron status is higher in the substantia nigra than in other brain regions but can fluctuate as function of diet and genetics and disease. Of particular note is the compartmentalization of the iron-enrichment in this region; the pars reticulata contains higher levels of stainable iron as compared to the pars compacta. The latter area is where the dopaminergic neurons reside. How this compartmentalization impacts the interpretation of data that iron contributes to cell death as in… CONTINUE READING

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