Iron, iron-binding proteins and immune system cells.

  title={Iron, iron-binding proteins and immune system cells.},
  author={Maria Leonor Baptista de Sousa and F Breedvelt and Roselynn Dynesius-Trentham and David E Trentham and John Lum},
  journal={Annals of the New York Academy of Sciences},
In summary, the work reviewed in the present paper indicates that 1. Iron and the iron-binding proteins can act as regulators of immune function, and not only as a result of a nutritional dependence of lymphoid cells on transferrin and transferrin-iron. Subsets of cells of the immune system respond differently to increases in iron concentration in vitro and in vivo. 2. Macrophages and lymphocytes differ in the H and L subunit content of the ferritins synthesized in response to increases in iron… CONTINUE READING


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