Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humans

@article{Huh2014IrisinSM,
  title={Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humans},
  author={Joo Young Huh and Fadime Dincer and Ertirea T Mesfum and C S Mantzoros},
  journal={International Journal of Obesity},
  year={2014},
  volume={38},
  pages={1538-1544}
}
Background:Irisin is a recently identified exercise-induced myokine suggested to induce browning of white adipocytes. Deficiency of myostatin, and thus stimulation of muscle growth, has also been reported to induce irisin and its precursor FNDC5 expression in muscle and drive the browning of white adipocytes in mice, implying that irisin may be related to… CONTINUE READING