Irinotecan-involved regimens for advanced gastric cancer: a pooled-analysis of clinical trials.

@article{Wang2010IrinotecaninvolvedRF,
  title={Irinotecan-involved regimens for advanced gastric cancer: a pooled-analysis of clinical trials.},
  author={D Wang and Dong-Ying Gu and Hua-Ying Huang and Zhi Biao Xu and Jinfei Chen},
  journal={World journal of gastroenterology},
  year={2010},
  volume={16 46},
  pages={5889-94}
}
AIM To assess the efficiency and toxicities of irinotecan (CPT-11)-involved regimens in patients with advanced gastric cancer. METHODS Randomized phases II and III clinical trials on chemotherapy for advanced gastric cancer were searched from MEDLINE, EMbase, Cochrane Controlled Trials Register, and EBSCO. Relevant abstracts were manually searched. A total of 657 patients were analyzed for their overall response rate (ORR), time to treatment failure (TTF), overall survival (OS) rate, and… CONTINUE READING