Irinotecan during pregnancy in metastatic colon cancer.

  title={Irinotecan during pregnancy in metastatic colon cancer.},
  author={Massimo Cirillo and Mariella Musola and Paola Agnese Cassandrini and Gianluigi Lunardi and Marco Venturini},
  volume={98 6},
BACKGROUND Colon cancer during pregnancy is a relatively rare occurrence. To date there has been sparse clinical evidence about the safety of chemotherapy in this setting because the available data derive only from single-institution case reports. METHODS Irinotecan and fluorouracil, as part of the FOLFIRI regimen, were administered to a 33-year-old pregnant woman at an estimated gestational age of 23+ weeks. She had been diagnosed with adenocarcinoma of the transverse colon with liver and… CONTINUE READING
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