Iridium-catalyzed H/D exchange: ligand complexes with improved efficiency and scope.


Hydrogen isotope exchange (HIE) is one of the most attractive tools for the introduction of deuterium or tritium to an organic compound. Herein, iridium complexes with N,P-ligands, highly active catalysts for asymmetric double bond reductions, have been tested for their HIE capabilities. Electron-rich ligands, containing dicyclohexylphosphines or… (More)
DOI: 10.1002/chem.201402078