Irbesartan, an angiotensin receptor blocker, exhibits metabolic, anti-inflammatory and antioxidative effects in patients with high-risk hypertension

@article{Taguchi2013IrbesartanAA,
  title={Irbesartan, an angiotensin receptor blocker, exhibits metabolic, anti-inflammatory and antioxidative effects in patients with high-risk hypertension},
  author={Isao Taguchi and Shigeru Toyoda and Kazuhiko Takano and Takuo Arikawa and Migaku Kikuchi and Mikie Ogawa and Shichiro Abe and Koichi Node and Teruo Inoue},
  journal={Hypertension Research},
  year={2013},
  volume={36},
  pages={608-613}
}
Irbesartan, an angiotensin II receptor blocker (ARB), acts as a selective PPAR-γ (peroxisome proliferator-activated receptor-γ) modulator, and thus may have anti-inflammatory and antioxidative effects, as well as beneficial effects on glucose and lipid metabolism. We enrolled 118 high-risk hypertensive outpatients, defined as those with the presence of at least one complication such as coronary artery disease, cerebrovascular disease or diabetes, and who were receiving any ARB except for… CONTINUE READING

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