Ipsilateral cortical fMRI responses after peripheral nerve damage in rats reflect increased interneuron activity.

@article{Pelled2009IpsilateralCF,
  title={Ipsilateral cortical fMRI responses after peripheral nerve damage in rats reflect increased interneuron activity.},
  author={Galit Pelled and Debra A Bergstrom and Patrick L. Tierney and Richard S Conroy and Kai-Hsiang Chuang and David Yu and David A. Leopold and Judith R. Walters and Alan P. Koretsky},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2009},
  volume={106 33},
  pages={14114-9}
}
In the weeks following unilateral peripheral nerve injury, the deprived primary somatosensory cortex (SI) responds to stimulation of the ipsilateral intact limb as demonstrated by functional magnetic resonance imaging (fMRI) responses. The neuronal basis of these responses was studied by using high-resolution fMRI, in vivo electrophysiological recordings, and juxtacellular neuronal labeling in rats that underwent an excision of the forepaw radial, median, and ulnar nerves. These nerves were… CONTINUE READING