Ipsapirone neuroendocrine challenge: relationship to aggression as measured in the human laboratory.

@article{Moeller1998IpsapironeNC,
  title={Ipsapirone neuroendocrine challenge: relationship to aggression as measured in the human laboratory.},
  author={F. Gerard Moeller and Terri J Allen and D R Cherek and Donald M. Dougherty and Scott D. Lane and Alan C. Swann},
  journal={Psychiatry research},
  year={1998},
  volume={81 1},
  pages={31-8}
}
Thirty-one human subjects were administered a neuroendocrine challenge with the 5-HT1a agonist ipsapirone after completing six sessions of a laboratory measure of aggression, the Point Subtraction Aggression Paradigm (PSAP), in order to determine if a laboratory measure of aggression was related to serotonin function. Subjects who showed more aggressive responding on the PSAP (n = 11) had a significantly blunted temperature response to ipsapirone compared to those with less aggressive… CONTINUE READING