Ipratropium nasal spray in children with perennial rhinitis.

  title={Ipratropium nasal spray in children with perennial rhinitis.},
  author={Eli O Meltzer and H Alice Orgel and Roberto Biondi and John W. Georgitis and Henry Milgrom and Z M Munk and Julius H van Bavel and Chester C Wood and Kristin Drda},
  journal={Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology},
  volume={78 5},
OBJECTIVE To compare the efficacy and safety of ipratropium nasal spray and placebo administered twice each day for 4 weeks in pediatric patients with perennial rhinitis who had rhinorrhea as a major complaint. METHODS This was a multicenter, double-blind, parallel group study. Patients aged 6 to 18 years with symptoms of perennial nonallergic (PNAR) or perennial allergic rhinitis (PAR) were randomized to receive ipratropium (42 micrograms per nostril) or placebo nasal spray, double-blind… CONTINUE READING


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