Iontophoretic vincristine in the treatment of postherpetic neuralgia: a double-blind, randomized, controlled trial.

@article{Dowd1999IontophoreticVI,
  title={Iontophoretic vincristine in the treatment of postherpetic neuralgia: a double-blind, randomized, controlled trial.},
  author={Noreen P Dowd and Fergal Day and D Timon and Alastair J Cunningham and Lawrence Brown},
  journal={Journal of pain and symptom management},
  year={1999},
  volume={17 3},
  pages={175-80}
}
The effect of iontophoretic administration of vincristine in the treatment of postherpetic neuralgia (PHN) was investigated in a prospective, double-blind, placebo-controlled trial. Twenty patients with intercostal or lumbar PHN for more than 6 months that was unresponsive to conventional medical therapy were randomized to receive vincristine 0.01% (n = 11) or saline (n = 9), by iontophoresis over 1 hour daily for 20 days. Demographics and median duration of pain were similar in both groups… CONTINUE READING