Iontophoretic delivery of calcium for experimental hydrofluoric acid burns

@article{Yamashita2001IontophoreticDO,
  title={Iontophoretic delivery of calcium for experimental hydrofluoric acid burns},
  author={Masatomo Yamashita and Masatomo Yamashita and M Suzuki and H Hirai and Hiroshi Kajigaya},
  journal={Critical Care Medicine},
  year={2001},
  volume={29},
  pages={1575-1578}
}
ObjectiveTo examine the efficacy of iontophoretic delivery of calcium to experimental hydrofluoric acid burns. DesignProspective, controlled study. SettingInstitutional laboratory. SubjectsMale nude rats. InterventionsFor the in vitro experiment, a full-thickness skin from the back was set in a vertical flow-through diffusion cell. Calcium chloride was applied to the donor chamber, and transdermal transport of calcium was examined with or without a voltage gradient of 1.5 V. Either intact skin… 
Clinical arterial infusion of calcium gluconate: The preferred method for treating hydrofluoric acid burns of distal human limbs
TLDR
Arterial infusion of calcium gluconate, effectively relieving the pain, blocking wound progressive deepening, and causing no adverse effects, could be the preferential method to treat hydrofluoric acid burns of the distal human limbs.
Clinical arterial infusion of calcium gluconate: the preferred method for treating hydrofluoric acid burns of distal human limbs.
TLDR
Arterial infusion of calcium gluconate, effectively relieving the pain, blocking wound progressive deepening, and causing no adverse effects, could be the preferential method to treat hydrofluoric acid burns of the distal human limbs.
Transdermal iontophoresis: combination strategies to improve transdermal iontophoretic drug delivery.
PHYSICAL PENETRATION ENHANCEMENT BY IONTOPHORESIS: A REVIEW
TLDR
Iontophoresis seems to be an ideal candidate to sort out the limitations associated with  the delivery of ionic drugs, including history, types, andvarious factors affecting the drug del delivery and applications.
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TLDR
The payback of using iontophoretic technique includes improved systemic bioavailability ensuing from bypassing the first metabolism andVariables due to oral administration, such as pH, the presence of food or enzymes and transit times can all be eliminated.
A review of treatment strategies for hydrofluoric acid burns: current status and future prospects.
IONTOPHORESIS: AN APPROACH TO DRUG DELIVERY ENHANCEMENT
TLDR
The flux associated with iontophoretic treatment is described along with its applications in the article and the future aspects of iontophile treatment and the medications currently available are included in this article.
Chemical burn injury due to hydrofluoric acid: a case of successful management without hexafluorine
TLDR
The patient was admitted to the authors' burn center with second and third degree burn injuries over 5% of his body and the burn improved completely and dramatically without application of hexafluorine because he presented to the burn center expeditiously.
Hydrofluoric acid on dentin should be avoided.
Possible hazardous effects of hydrofluoric acid and recommendations for treatment approach: a review
TLDR
The present study offers a review of chemical properties of HF used, highlight the possible hazardous effects of this agent, and to recommend the treatment approach for potential risks.
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