Iontophoretic administration of S(+)-ketamine in patients with intractable central pain: A placebo-controlled trial

@article{Vranken2005IontophoreticAO,
  title={Iontophoretic administration of S(+)-ketamine in patients with intractable central pain: A placebo-controlled trial},
  author={Jan H. Vranken and Marcel G. W. Dijkgraaf and M R Kruis and Nick T. van Dasselaar and M Vegt},
  journal={Pain},
  year={2005},
  volume={118},
  pages={224-231}
}
The efficacy of 50 and 75 mg S(+)-ketamine administered daily by an iontophoresis-assisted transdermal drug delivery system was tested against placebo in a randomized, double-blind design in 33 patients with central neuropathic pain. At baseline and 1 week after the start of treatment subjects were evaluated with standard measures of efficacy: pain intensity measured by visual analog scale (VAS), health status (Pain Disability Index and EQ-5D) and quality of life (SF-36). Safety assessment… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Similar Papers

Loading similar papers…