Iontophoretic Delivery of 5-Aminolevulinic Acid (ALA): Effect of pH

  title={Iontophoretic Delivery of 5-Aminolevulinic Acid (ALA): Effect of pH},
  author={Renata Fonseca Vianna Lopez and Maria Vit{\'o}ria Lopes Badra Bentley and M. Bego{\~n}a Delgado-Charro and Richard Guy},
  journal={Pharmaceutical Research},
Purpose. To examine the iontophoretic delivery of ALA as a function of pH and to determine the principal mechanisms responsible for its electrotransport. Methods. Anodal iontophoretic transport of ALA was measured as a function of its concentration and pH of the donor solution. Experiments were performed in vitro using skin excised from porcine ears as the… CONTINUE READING