Ionotropic glutamate receptor binding in the posterior cingulate cortex in schizophrenia patients

@article{Newell2005IonotropicGR,
  title={Ionotropic glutamate receptor binding in the posterior cingulate cortex in schizophrenia patients},
  author={Kelly A Newell and Katerina Zavitsanou and Xu-Feng Huang},
  journal={NeuroReport},
  year={2005},
  volume={16},
  pages={1363-1367}
}
Using quantitative autoradiography, the present study examined ionotropic glutamatergic receptor binding sites using [3H]dizocilpine, [3H]&agr;-amino-3-hydroxy-5-methylisoxazole-4-propionate, and [3H]kainate in the posterior cingulate cortex of schizophrenia patients and matched controls. We found a significant increase in [3H]dizocilpine binding in the superficial layers (41%, p<0.001) and deep layers (30%, p=0.004) of the posterior cingulate cortex in the schizophrenia group compared with… 

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