Ionizing radiation-induced bystander effects, potential targets for modulation of radiotherapy.

@article{RzeszowskaWolny2009IonizingRB,
  title={Ionizing radiation-induced bystander effects, potential targets for modulation of radiotherapy.},
  author={Joanna Rzeszowska-Wolny and Waldemar M. Przybyszewski and Maria Widel},
  journal={European journal of pharmacology},
  year={2009},
  volume={625 1-3},
  pages={156-64}
}
Cells exposed to ionizing radiation show DNA damage, apoptosis, chromosomal aberrations or increased mutation frequency and for a long time it was generally accepted that these effects resulted from ionization of cell structures and the action of reactive oxygen species formed by water radiolysis. In the last few years, however, it has appeared that cells exposed to ionizing radiation and other genotoxic agents can release signals that induce very similar effects in non-targeted neighboring… CONTINUE READING