Ionizing radiation can overcome resistance to TRAIL in TRAIL-resistant cancer cells.

@article{Kim2001IonizingRC,
  title={Ionizing radiation can overcome resistance to TRAIL in TRAIL-resistant cancer cells.},
  author={Minki Kim and Jun Young Lee and Moon Taek Park and Yong Jin Chun and Ye Jin Jang and Chang Mo Kang and Hee Sun Kim and Chong Kwan Cho and Yun Sil Lee and Ha Yeon Jeong and Su - Jae Lee},
  journal={FEBS letters},
  year={2001},
  volume={505 1},
  pages={
          179-84
        }
}
Although the majority of cancer cells are killed by TRAIL (tumor necrosis factor-related apoptosis-inducing ligand treatment), certain types show resistance to it. Ionizing radiation also induces cell death in cancer cells and may share common intracellular pathways with TRAIL leading to apoptosis. In the present study, we examined whether ionizing radiation could overcome TRAIL resistance in the variant Jurkat clones. We first selected TRAIL-resistant or -sensitive Jurkat clones and examined… CONTINUE READING
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