Ionizing Radiation, DNA Double Strand Break and Mutation

Abstract

Ionizing radiation has been proved a major stress that can induce carcinogenesis. Nuclear DNA is the main target of ionizing radiation, exposure of which is followed by many types of DNA damages. DNA double-strand breaks (DSBs) induced by ionizing radiation are considered the most relevant lesion for mutations and carcinogenesis, and unrepaired or… (More)

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