Ionisation characteristics and elimination rates of some aminoindanones determined by capillary electrophoresis.

@article{Simplcio2004IonisationCA,
  title={Ionisation characteristics and elimination rates of some aminoindanones determined by capillary electrophoresis.},
  author={Ana Lu{\'i}sa Simpl{\'i}cio and John F. Gilmer and Neil H Frankish and Helen Sheridan and John J. Walsh and John M Clancy},
  journal={Journal of chromatography. A},
  year={2004},
  volume={1045 1-2},
  pages={233-8}
}
Capillary electrophoresis (CE) has emerged as an important tool for evaluating the ionisation characteristics of compounds and their corresponding pKa values. A particular strength of CE in this context is that its relative selectivity allows one to measure the extent of ionisation of materials that are impure. In this study, using CE, we have measured the pKa values of a series of anti-inflammatory aminoindanones, which underwent degradation to indenone during the course of the determination… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
2 Extracted Citations
0 Extracted References
Similar Papers