Ionic mechanisms associated with the depolarization by glutamate and aspartate on human and rat spinal neurones in tissue culture

@article{Hsli1976IonicMA,
  title={Ionic mechanisms associated with the depolarization by glutamate and aspartate on human and rat spinal neurones in tissue culture},
  author={Leo H{\"o}sli and Pedro Andr{\'e}s and Elisabeth H{\"o}sli},
  journal={Pfl{\"u}gers Archiv},
  year={1976},
  volume={363},
  pages={43-48}
}
The action of glutamate and aspartate was studied on the membrane potential of human and rat spinal neurones in tissue culture. Both amino acids caused a depolarization of the cell membrane, the size of which was dependent on the concentration of the amino acids in the bathing fluid. In order to study ionic mechanisms associated with the amino acid depolarization, the ionic composition of the extracellular fluid was altered. Removal of sodium ions from the bathing solution reversibly reduced or… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 33 references

Effect of potassium and sodium on resting and action potentials of single myelinated nerve fibres

  • A. F. Huxley, R. St impfli
  • J . Physiol . ( Lond . )
  • 1975

Amino acid transmittersaction and uptake in neurones and glial cells of human rat CNS tissue cultures

  • P. F. AndrOs, J. R. Wolff
  • Golgi Centennial Symposium : Perspectives in…
  • 1974

Electrophysiological and histochemical properties of fetal human spinal cord in tissue culture

  • Y. Zottermann
  • 1973

Similar Papers

Loading similar papers…