Ionic mechanisms and Ca2+ handling in airway smooth muscle.

@article{Hirota2007IonicMA,
  title={Ionic mechanisms and Ca2+ handling in airway smooth muscle.},
  author={Simon A Hirota and Peter B Helli and Luke Jeffrey Janssen},
  journal={The European respiratory journal},
  year={2007},
  volume={30 1},
  pages={114-33}
}
Asthma is a disease characterised by reversible contraction of airway smooth muscle. Many signalling pathways are now known to underlie that contraction, almost all of which revolve around Ca(2+) handling. Ca(2+) homeostasis in turn is governed by a wide variety of ionic mechanisms, which are still poorly understood. The present review will briefly summarise those mechanisms that have been recognised for decades, but will then devote considerable attention to several novel ionic signalling… CONTINUE READING

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References

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Showing 1-10 of 187 references

A method for determining the dependence of calcium oscillations on inositol trisphosphate oscillations.

Proceedings of the National Academy of Sciences of the United States of America • 2006

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