Ionic liquids/[bmim][N3] mixtures: promising media for the synthesis of aryl azides by SNAr.

@article{DAnna2008IonicLM,
  title={Ionic liquids/[bmim][N3] mixtures: promising media for the synthesis of aryl azides by SNAr.},
  author={Francesca D'Anna and Salvatore Marullo and Renato Noto},
  journal={The Journal of organic chemistry},
  year={2008},
  volume={73 16},
  pages={
          6224-8
        }
}
The nucleophilic aromatic substitution of some activated aryl or heteroaryl halides has been performed in ionic liquid solution, using the 1-butyl-3-methylimidazolium azide as a nucleophile. The reaction course was studied varying the structures of both substrates and ionic liquids. In particular, in the latter case, the reaction of 2-bromo-5-nitrothiophene was carried out in five different ionic liquids ([bmim][BF 4], [bmim][PF 6], [bmim][NTf 2], [bm 2im][NTf 2], and [bmpyrr][NTf 2]). Finally… CONTINUE READING
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