Ionic currents in single isolated bullfrog atrial cells

  title={Ionic currents in single isolated bullfrog atrial cells},
  author={Joseph R. Hume and Wayne Giles},
  journal={The Journal of General Physiology},
  pages={153 - 194}
Enzymatic dispersion has been used to yield single cells from segments of bullfrog atrium. Previous data (Hume and Giles, 1981) have shown that these individual cells are quiescent and have normal resting potentials and action potentials. The minimum DC space constant is approximately 920 microns. The major goals of the present study were: (a) to develop and refine techniques for making quantitative measurements of the transmembrane ionic currents, and (b) to identify the individual components… CONTINUE READING


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